Debromination of endo-(+)-3-Bromocamphor with Primary Amines
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چکیده
A desbromação redutiva da endo-(+)-3-bromocânfora com diferentes aminas primárias seguida da formação de imina foi investigada. Esta reação requer procedimento experimental simples sem qualquer solvente orgânico, metal ou agente de redução convencional. Observou-se uma forte influência da polaridade da amina na eficiência do processo de desbromação, e que etanolamina e etilenodiamina tendo pontos de ebulições elevados o suficiente podem desbromar 3-bromocânfora fornecendo canfoniminas em bons rendimentos. Os mecanismos de desbromação da 3-bromocânfora com etanolamina e n-hexilamina foram investigados no nível B3LYP/6-311+G(d,p). Revelou-se o mecanismo radical, e que a reação com etanolamina mais polar é energeticamente mais favorável.
منابع مشابه
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تاریخ انتشار 2013